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Methadone is prescribed for pain relief, to treat opiate addiction and for some other conditions such as obesity. Methadone is a potent opiate, as its primary metabolite morphine is a strong analgesic. Methadone highly potent drug, as a large percentage of the drug that enters body from the intestinal tract is metabolized by the liver into morphine. Methadone therefore causes withdrawal in many cases, as the opioid receptor in brain, spinal cord and other parts of the body is now activated. In addition, the amount of opiate drugs that can be taken increases significantly with use of methadone.
Injecting opiates can produce severe adverse effects on the kidneys and liver. As with almost all prescription opiates, the first signs of abuse can be found when someone is injecting opiates for the first time. As with every other opiate, the more that people use heroin, the more likely they are to become dependent on prescription drugs. The same is true for methadone and other opiate drugs. The more that people use methadone or other opiate drugs, the more likely their bodies are to respond these drugs with dependence. This has occurred for many as they began taking methadone a replacement for prescription opiates. In a 2008 survey by The Washington Post, rate of methadone dependent people was 3.6%.
The most severe and dangerous consequences of methadone use can be associated with the rapid rise in rates of fatalities and hospitalizations. The FDA has issued warnings to doctors, nurses and social workers about problems with overdose and death from methadone use.
Injecting methadone can produce profound changes in the body such as increased sweating and other signs of cardiovascular problems such as increased heart rate and blood pressure. Also, methadone itself causes a significant weight loss. However, the use of high doses methadone with a variety of other drugs can lead to severe and even life-threatening withdrawal symptoms. A period from methadone of three to ten weeks can occur without treatment if not properly managed.
Methadone can cause an addiction with a person who was addicted to opiates but who became "cannabis-dependent". In this case, a person addicted to opiates may become marijuana. This is seen commonly in former heroin addicts who no longer produce enough heroin while continuing to receive methadone or other opiates.
Methadone is frequently mixed with heroin, causing a high risk of fatal toxicity. Although the overdose risk of taking heroin and methadone is similar, the danger caused by combining drugs is greater. If this was not the case, a heroin overdose would be less worrisome when overdosing with methadone.
A person has greater risk of dying when taking heroin with methadone than any other opioid. The risk of overdose is highest when methadone has been combined with heroin.
There is a greater risk of overdose when the person has had a heroin problem before, while taking both heroin and methadone. The risk Deltasone 20 mg
is elevated for anyone who has previously been treated for heroin dependence, or is taking it as a replacement for prescription opiates.
When the person taking methadone dies from an overdose associated with methadone mixed heroin, symptoms may include vomiting, diarrhea, low blood pressure, cardiac arrhythmia, convulsions, renal failure and rapid breathing. These symptoms are usually similar to those of an overdose with heroin or morphine. The symptoms of methadone overdose have.
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